1-[3-(Trifluoromethyl)phenyl]cyclopropanamine is an organic compound with the chemical formula C10H10F3N. It is a white to pale yellow solid.
Nature:
1-[3-(Trifluoromethyl)phenyl]cyclopropanamine has a benzene ring and cyclopropylamine structure. Its nitrogen atom contains a lone pair of electrons and belongs to an important amine compound. Its main properties are as follows:
-Melting point: about 52-54 ℃
-Boiling point: about 256-258 ℃
-Solubility: 1-[3-(Trifluoromethyl)phenyl]cyclopropanamine can be dissolved in water and common organic solvents under acidic and alkaline conditions.
Use:
1-[3-(Trifluoromethyl)phenyl]cyclopropanamine have a variety of applications in pharmacy and agriculture:
-Drug intermediate: As an intermediate for the synthesis of biologically active organic molecules, such as drugs or biologically active substances.
-Pesticides: Can be used to synthesize some pesticides for agricultural applications such as insecticide, sterilization or weeding.
Preparation Method:
The preparation of 1-[3-(Trifluoromethyl)phenyl]cyclopropanamine can be carried out by the following steps:
1. Synthesis of 3-trifluoromethylpropiophenone (3-Trifluoromethyl acetophenone).
2. Under alkaline conditions, 3-trifluoromethylpropiophenone reacts with cyclopropylamine to generate 1-[3-(Trifluoromethyl)phenyl]cyclopropanamine. The reaction can be carried out under solution or solid conditions.